PIK3CA p.E545D Reference Standard
CBP10623
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| Introduction | |
| Format | Genomic DNA |
| Description | PIK3CA E545D is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545D results in increased transFormation ability in two different cell lines in culture, and therefore, is predicted to lead to a gain of Pik3ca protein function. |
| Technical Data | |
| DNA Change: | c.1635G>T |
| AA Change | p.E545D |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 49.7%（DdPCR） |
| Transcript | NM_006218.4 |
| Chr position(GRCh37) | chr3:178936093 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
